PCL 7: The Wedding

PCL 7: THE WEDDING
Patient’s Details
Name : Sumey
Gender : Female, Indian
Age : 28
Occupation : ??

CC : Loss of weight with palpitations
Associated:
• Tremors
• Eyes look different
• Glandular swelling (not sure where???)
• Loss of fat and muscle
• Increased appetite
• LOSS OF WEIGHT WITH NO LOSS OF APPETITE
Family Hx: Father had a MI
Social Hx:
• Likes to go travelling
• Drinks occasionally
• No smoking
DDx:
• Hyperthyroidism
• Malabsorption
• Diabetes
• STRESS
• Malignancy

LEARNING ISSUES:
1. DDx (4)
o Malabsorption- Shamendri
o Diabetes- Fui Chen
o STRESS- Kieron
o Malignancy (Abdominal) - David
2. Anatomy and physiology of thyroid gland (2)- Lukman and Samantha
3. Pathophysiology of hyperthyroidism (1)- Nicole
4. Signs and Symptoms (1)- Viran
5. Investigations (1)- Rose
6. Treatment and management (1)- Syukriah
7. Complications and Psychosocial (1)- Deep
PLEASE SEND TO DR WONG BY 16th September (12PM) cheepiau@gmail.com

DISCUSSION OF THE LAST PCL!!

about the negative feedback
receptor is not sensitive
there is no end product, so no negative feedback..

how cushing syndrome led to osteoporosis (increased cortisol)
proximal muscle weakness (increased cortisol)

HOW THESE HAPPEN?

discuss this..!!
Viran

PCL 6: NO MORE DIETS

Patient’s Details
Name : SITI
Gender : Female, Malay
Age : 43
Occupation : ??

CC : WEIGHT GAIN associated with:-
• Red (plethora/malar rash/alcoholic/sun burn/flushing) face - vasodilatation
• Round face
• Bruise
• Pimples
• Moustache (hirsutism) - due to androgen? Androgen comes from testosterone?
SYSTEMIC FEATURES – possibly due to hormone (steroids?)
PH : Hypertension (on medication?)
Social : Watching on diet

HORMONES
 Chemical messengers
 Travel in the blood
 Affect multiple organs
 Examples: insulin, sex hormones (testosterone), growth hormones, oxytoxin, progesterone, thyroxine, ADH, ACTH, cortisol, prolactin, TSH, FSH, LH, etc.

LEARNING ISSUE
1. Hormonal control – pituitary axis & non-pituitary axis glandsorgans
a. Negative-positive feedback (3)
2. Epidemiology
3. Cushing’s Syndrome (1) and Cushing’s Disease (1)
4. Differential Diagnosis (3) – PCOS, ….
5. Pathophysiology of hormonal control (2)
6. Investigation
7. Treatment and Management
8. Complications & Psychosocial

1. Endocrine system – endocrine control, negative-positive feedback mechanism
a. Pituitary axis
b. Non-pituitary axis (Nicole, Kieron, Deepak)
2. Pathophysiology of endocrine system- how does the endocrine system go wrong? (Viran, Shamendri)
3. Differential Diagnosis (Lukman, Sam)
a. PCOS
b. Etc.
4. Cushing Syndrome + Disease (4)
a. Definition + Epidemiology (Fui Chen)
b. Risk Factors & Causes
c. Signs & Symptoms (Syurkriah)
d. Investigations/Diagnosis
e. Treatment & Management (David)
f. Complications & Psychosocial (Rose)


PLEASE SEND TO DR WONG BY WEDNESDAY (12PM) cheepiau@gmail.com

Anatomy: Abdomen V

1.1 - 1.4 Viran
1.5 - 1.7 Fui Chen
2.1 - 2.5 Nicole
3.1 - 3.4 Shamendri
4.1 - 4.3 Lukman
4.4 - 4.5 Sam
5.1 - 5.4 Rose
5.5 - 5.9 Kieron
6.1 - 6.3 Deepak
6.4 - 6.5 Syukriah
6.6 - 6.7 David
7.1 - 7.4 Rose

WEEK 4: ABDOMEN IV

It's time for task delegation!!!! =)

1- Fui Chen (1.1-1.3) + Syukriah (1.4-1.6)

2- Sam (2.1-2.5) + David (2.6-2.7)

3- Rose

4- Kieron

5- Nicole

6- Luqman

7- Viran (7.1-7.4) + Deepak (7.5-7.7)

8- Shamendri